What are the methodological challenges specific to evaluating digital therapeutics in an open-label setting?

In an open-label trial the identity of treatment is known to all. The double-blind trial is the optimal approach. This requires that the treatments to be ... Sep 17, 2024 ... Sarah Howlett discussing the trial design of STAMPEDE2, a phase 3, randomized, open-label trial of niraparib-abiraterone acetate + prednisolone ... A seven-week, open-label trial evaluating the safety and efficacy of a photopneumatic device for mitigating mild-to-moderate acne in healthy adolescents and ... Mar 8, 2021 ... The findings show that treating COVID-19 patients with an injection of 100 milligrams of anakinra for ten days may be an effective approach because the drug ... Treating Foot Infections in Diabetic Patients: A Randomized, Multicenter, Open-Label Trial of Linezolid versus Ampicillin-Sulbactam/Amoxicillin-Clavulanate. A randomized, multicenter, open-label trial to determine peritonitis rate, product defect, and technique survival between ANDY-Disc® and UltraBag® in patients ... Open-label trial of Sibeprenlimab for treatment of IgAN. Research type. Research Study. Full title. A Phase 2/3, Multicenter, Open-label Trial to Evaluate the ... May 2, 2023 ... A phase II open-label trial of avelumab plus axitinib in previously treated non-small-cell lung cancer or treatment-naïve, cisplatin ... May 23, 2014 ... Open label trials are sometimes referred to as “non-masked” or “unblinded.” If the trial is a non-pharmacological study, such as a trial of ... Open-Label Trial pronounce term ... A type of clinical trial. In open-label trials, both the researchers and participants know which drug (or other intervention) ...