What are the methodological challenges in conducting comparative effectiveness research in an open-label setting?

Dec 1, 2003 ... ... open-label trial. James Cheng-Chung Wei, Tsai Wen Chan, Huey-Shyan Lin, Feng Huang and Chan-Te Chou. The Journal of Rheumatology December ... A multicenter, single-arm, open-label trial of birociclib, a CDK4/6 inhibitor, as a single agent, in patients with refractory HR+/HER2- metastatic breast ... Sep 17, 2024 ... ... Open-Label Trial in Patients with Newly Diagnosed Oligometastatic Prostate Cancer Starting ADT ... The STAMPEDE2 trial is a phase III, randomized, ... Perlmutter Cancer Center · Clinical Trials & Research Studies · Phase I open-label trial evaluating BI 1810631 as monotherapy in the treatment of patients with ... Apr 8, 2014 ... Multicentre, Randomised, Open-Label Trial To Compare Efficacy And Tolerance Of Prednisone And IVIG In Patients With CIDP On A One Year Follow Up ... Apr 20, 2023 ... Open-label clinical trials are appropriate when randomization of treatments may be difficult, or if it's important to test long-term effects or safety profiles. Open-Label Trial ... An open-label trial is a type of study where both the participants and the investigators are aware of the treatment being provided. It is ... This is a phase 2/3 open-label trial to evaluate the long-term safety, tolerability, and efficacy of sibeprenlimab administered subcutaneously (SC) in subjects ... Jun 17, 2023 ... Treatment with amikacin liposome inhalation suspension (ALIS) improve culture conversion in patients with M abscessus pulmonary disease. Nov 9, 2020 ... A randomized, open-label controlled trial of oral favipiravir in adults hospitalized with moderate to severe COVID-19 pneumonia from June 22nd 2020 to August ...