What are the limitations of subgroup analyses in open-label trials?

Jan 4, 2024 ... Participants were randomly assigned to treatment with the glucagon-like peptide 1 receptor agonist semaglutide or the sodium–glucose cotransporter 2 inhibitor ... The purpose of this preliminary study is to examine the active music therapy on cognition and neuropsychiatric symptoms in the elderly with mild and moderate ... Triheptanoin dramatically reduced by 90% the number of non-epileptic paroxysmal manifestations over 2 months in GLUT1-DS and improved patient's brain energy ... A randomized, open-label, clinical trial examined the effects of canagliflozin on albuminuria and eGFR decline using an individual pre-intervention eGFR slope. This project is being done to test the combination of Loncastuximab Tesirine along with a drug regimen called DA-EPOCH-R for patients with previously ... Perlmutter Cancer Center · Clinical Trials & Research Studies · Phase I open-label trial evaluating BI 1810631 as monotherapy in the treatment of patients with ... The Lancet Publishes Data from Phase 2, Open-Label Trial of Spinraza (Nusinersen) in Infants ... Today, Lancet published results from the Phase 2, open-label ... May 23, 2014 ... Open label trials are sometimes referred to as “non-masked” or “unblinded.” If the trial is a non-pharmacological study, such as a trial of ... Mar 8, 2024 ... This randomized open-label trial aimed to replicate this result in a sample of patients with risk factors for stroke (RFS). METHODS. Twenty ... Open-Label Trial ... An open-label trial is a type of study where both the participants and the investigators are aware of the treatment being provided. It is ...