What are the considerations when comparing outcomes in an open-label trial to historical data?

Apr 8, 2014 ... Multicentre, Randomised, Open-Label Trial To Compare Efficacy And Tolerance Of Prednisone And IVIG In Patients With CIDP On A One Year Follow Up ... Jun 10, 2011 ... An Open-Label Trial of Risperidone in Children and Adolescents with Severe Mood Dysregulation. Authors: Fernanda Valle Krieger, Gabriel ... Clinical trial for ALT | Non-Alcoholic Fatty Liver Disease | Non Insulin Dependent Diabetes , A Prospective, Randomized, Open Label Trial of Two Doses of ... Mar 4, 2018 ... An exploratory time-varying product-adherence analysis in which adherence was defined as a residual level of 21 mg or less of dapivirine in the ... Aug 3, 2022 ... Methods: In this open-label trial, 31 young people aged 12–25 years with a DSM-5 anxiety disorder and no clinical improvement despite treatment ... This project is being done to test the combination of Loncastuximab Tesirine along with a drug regimen called DA-EPOCH-R for patients with previously ... Jul 31, 2024 ... The main aim is to test how safe and effective the medicine ILUVIEN® (190μg) is for children and adolescents, who have non-infectious ... Jan 17, 2025 ... ... trial with randomized controlled treatment group assignment, open-label treatment, and blinded core laboratory outcome evaluation. This study ... NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Jul 9, 2021 ... Phase 1b open-label trial of afatinib plus Xentuzumab (BI 836845) in patients with EGFR mutation-positive NSCLC after progression on EGFR tyrosine kinase ...