What are the challenges in measuring quality of life in an open-label trial?

We describe two randomised trials where blinded outcome assessment was not possible, and discuss the strategies used to reduce the possibility of bias. Apr 25, 2024 ... "Results from this study show that patients with moderate-to-severe atopic dermatitis can strive for both little to no itch and clearer skin.” 1. May 29, 2024 ... Infusion of mbIL-7-TIL has acceptable safety and potent efficacy in recurrent OC patients who have limited treatment options. Jun 3, 2022 ... This open-label pilot study investigated whether practicing yoga in a class results in change in patients with alexisomia and alexithymia. A5384 is a trial for people who have or might have tuberculous meningitis (TBM). TBM is an infectious disease that causes inflammation of the membranes that ... Dec 21, 2021 ... A Phase 3 Prospective, Multicenter, Randomized, Open-Label Trial of Acalabrutinib Plus Venetoclax Versus Venetoclax Plus Obinutuzumab in Previously Untreated ... Treating Foot Infections in Diabetic Patients: A Randomized, Multicenter, Open-Label Trial of Linezolid versus Ampicillin-Sulbactam/Amoxicillin-Clavulanate. For this reason, extreme care needs to be taken regarding how subjects are randomized in open-label trials and randomization methods should be clearly explained ... Jan 4, 2024 ... Participants were randomly assigned to treatment with the glucagon-like peptide 1 receptor agonist semaglutide or the sodium–glucose cotransporter 2 inhibitor ... Jul 31, 2024 ... The main aim is to test how safe and effective the medicine ILUVIEN® (190μg) is for children and adolescents, who have non-infectious ...