What are the advantages and disadvantages of using adaptive designs in open-label trials?

Dec 1, 2023 ... Neurona Therapeutics Presents New Clinical Data from First Cohort in Ongoing Phase I/II Open-Label Trial of NRTX-1001 Cell Therapy for Drug- ... Jul 9, 2021 ... Phase 1b open-label trial of afatinib plus Xentuzumab (BI 836845) in patients with EGFR mutation-positive NSCLC after progression on EGFR tyrosine kinase ... In an open-label trial the identity of treatment is known to all. The double-blind trial is the optimal approach. This requires that the treatments to be ... Open-Label Trial pronounce term ... A type of clinical trial. In open-label trials, both the researchers and participants know which drug (or other intervention) ... A5384 is a trial for people who have or might have tuberculous meningitis (TBM). TBM is an infectious disease that causes inflammation of the membranes that ... SAT0471 Autologous Hematopoietic Stem Cell Transplantation in Rapidly Progressive Systemic Sclerosis is More Effective Than Conventional Therapies in Inducing D ... Apr 8, 2014 ... Multicentre, Randomised, Open-Label Trial To Compare Efficacy And Tolerance Of Prednisone And IVIG In Patients With CIDP On A One Year Follow Up ... Sep 17, 2024 ... ... Open-Label Trial in Patients with Newly Diagnosed Oligometastatic Prostate Cancer Starting ADT ... The STAMPEDE2 trial is a phase III, randomized, ... A randomized, open-label, clinical trial examined the effects of canagliflozin on albuminuria and eGFR decline using an individual pre-intervention eGFR slope. Oct 30, 2019 ... The study included children aged between 8 and 17 years, with moderate to severe psoriasis, given tofacitinib 5 mg orally twice daily for at least 36 weeks.