How can open-label trials be used to evaluate the feasibility of a new intervention?

Objective. Irritable bowel syndrome (IBS) is commonly comorbid with generalized anxiety disorder (GAD). We evaluated whether duloxetine would lead to ... Study #2024-1042. A Phase II multicenter open-label trial of tagraxofusp (Tag) in combination with venetoclax and azacitidine (Ven/Aza) in adults with ... Abstract. Purpose: Brentuximab vedotin (BV) is hypothesized to selectively deplete T regulatory cells that express CD30 and resensitize tumors to anti–PD-1 ... Dec 1, 2023 ... Neurona Therapeutics Presents New Clinical Data from First Cohort in Ongoing Phase I/II Open-Label Trial of NRTX-1001 Cell Therapy for Drug- ... A randomised controlled open label trial examining the safety of label-recommended semaglutide 1mg dose escalation vs a slower and flexible titration regimen. Oct 30, 2019 ... The study included children aged between 8 and 17 years, with moderate to severe psoriasis, given tofacitinib 5 mg orally twice daily for at least 36 weeks. Clinical trial for ALT | Non-Alcoholic Fatty Liver Disease | Non Insulin Dependent Diabetes , A Prospective, Randomized, Open Label Trial of Two Doses of ... Jan 1, 2025 ... This open-label study suggests efficacy and safety of psilocybin in severe TRD and supports further study of psychedelics in this population ... A randomized, open-label, clinical trial examined the effects of canagliflozin on albuminuria and eGFR decline using an individual pre-intervention eGFR slope. Jul 31, 2024 ... The main aim is to test how safe and effective the medicine ILUVIEN® (190μg) is for children and adolescents, who have non-infectious ...