How can open-label trials be designed to minimize the impact of placebo response?

Jun 17, 2023 ... Treatment with amikacin liposome inhalation suspension (ALIS) improve culture conversion in patients with M abscessus pulmonary disease. A randomised controlled open label trial examining the safety of label-recommended semaglutide 1mg dose escalation vs a slower and flexible titration regimen. Nov 2, 2023 ... Interim Analyses from the Beacon Trial: A Phase 2, Randomized, Open-Label Trial of Bitopertin in Erythropoietic Protoporphyria. Gayle Ross ... A randomized, multicenter, open-label trial to determine peritonitis rate, product defect, and technique survival between ANDY-Disc® and UltraBag® in patients ... Apr 20, 2023 ... Open-label clinical trials are appropriate when randomization of treatments may be difficult, or if it's important to test long-term effects or safety profiles. Nasal povidone-iodine may be considered as an alternative to mupirocin in a multifaceted approach to reduce SSI. Dec 1, 2003 ... ... open-label trial. James Cheng-Chung Wei, Tsai Wen Chan, Huey-Shyan Lin, Feng Huang and Chan-Te Chou. The Journal of Rheumatology December ... Mar 8, 2021 ... The findings show that treating COVID-19 patients with an injection of 100 milligrams of anakinra for ten days may be an effective approach because the drug ... A randomized, open-label, clinical trial examined the effects of canagliflozin on albuminuria and eGFR decline using an individual pre-intervention eGFR slope. An open-label randomised-controlled trial of azathioprine vs. mycophenolate mofetil for the induction of remission in treatment-naive autoimmune hepatitis.