Can genetic risk scores be used to identify individuals who might benefit most from early lifestyle interventions or pharmacological treatment?

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Many healthcare professionals now believe that determining your non-HDL cholesterol level may be more useful than calculating your cholesterol ratio. A pooled evaluation of 1,127 population-based studies comprising 102.6 million adults globally suggests an optimal non-HDL-C cholesterol of 70-85 mg/dL (1.8-2.2 ... Too much non-HDL leads to a build up of fatty deposits inside the walls of the blood vessels (channels that carry blood throughout your body). This builds up ... 2022;22(6):1025-1032 1025www.bjbms.orgINTRODUCTIONAbnormalities in serum lipids, including elevated blood low-density lipoprotein cholesterol (LDL-C), ... Feb 28, 2011 ... Non-HDL-C represents a simple surrogate for apoB in hypertriglyceridemic and/or T2DM patients. ApoB and non-HDL-C show high correlation. The objective of the study was to determine if Atherogenic Index (AI) and non-HDL-cholesterol are good risk predictors in DM patients. Aug 11, 2016 ... Objectives—. Non–high-density lipoprotein cholesterol (non-HDLC) levels reflect the full burden of cholesterol transported in atherogenic ... These studies suggest that elevated non-HDL cholesterol levels are associated with an increased risk of cardiovascular disease and should be monitored and ... secondary goal for non-HDL cholesterol (total – HDL) ... 30 mg/dL higher than LDL goal. Comparison of LDL Cholesterol and Non-HDL Cholesterol Goals for Three Risk ... Non-HDL-cholesterol/HDL-cholesterol is a better predictor of metabolic syndrome and insulin resistance than apolipoprotein B/apolipoprotein A1. Int J Cardiol, ...
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