What are the challenges in developing new and more effective laxatives

... laxative and drug-induced nephrotoxicity; and renal ischemia from severe ... Currently, bulk-forming laxatives, osmotic laxatives, and stimulant laxatives ... Laxative abuse was associated with worse eating disorder and general psychopathology and higher prevalence of borderline personality disorder (BPD). Laxative ... "Purgative" redirects here. For other uses, see Purgation. Laxatives, purgatives, or aperients are substances that loosen stools and increase bowel ... Mar 12, 2025 ... 12 Natural Laxatives to Eat for Constipation ... Natural laxatives, like papaya, oranges and plums, are great options that stimulate bowel ... Jun 30, 2023 ... The best laxative is the gentlest and safest option, like a bulk-forming laxative. If laxatives don't work, ask for help. Dec 1, 2005 ... Although stimulant laxatives are more effective than bulk-forming laxatives, they also are more likely to cause diarrhea and abdominal pain. Laxatives taken by mouth are available in liquid, tablet, gum, powder, and granule forms. They work in various ways. Jan 22, 2025 ... Types of laxatives for quick relief of constipation · Oral osmotic laxative · Preferred choice in children older than 6 months. Mar 19, 2020 ... The following is a list of the different types of laxatives and treatments available. It's best if your decision is guided by your healthcare provider. PHILLIPS'® LAXATIVE CAPLETS · How many Phillips' Caplets can I take for occasional constipation? Adults and children 12 years and older: Take 2-4 caplets daily.