What is the role of hyperpolarization in tinnitus?

Dec 4, 2017 ... We propose that these intracellular pathways are potential therapeutic targets for achieving depolarization/hyperpolarization (D/H) balance in psychiatric and ... experiments with CIDNP hyperpolarization. This setup has been described in detail in Ref. [52]. Two series of experiments were carried out: measurements of ... Hyperpolarized 13 C magnetic resonance spectroscopic (MRS) imaging has emerged as a complementary metabolic imaging approach. Jun 7, 2023 ... The purpose of this study is to assess the feasibility of an interleaved acquisition of 31 P MRSI and 23 Na MRI. Potassium ions reach equilibrium when the membrane voltage is below −70 mV, so a period of hyperpolarization occurs while the K+ channels are open. Hyperpolarization refers to a shift in a cell's membrane potential from positive to negative. It suppresses action potentials by increasing the amount of ... When the neurotransmitter molecules bind to ligand-gated ion channels on the receiving cell, they may cause depolarization of that cell, causing it to undergo ... Apr 4, 2022 ... Apparently the sodium potassium pump restores it following hyperpolarization, but I really can't imagine how it would do that! Mar 16, 2022 ... Accurate simulations show astonishingly rich and unexpected dynamics in SABRE/X-SABRE, which we explain with a combination of perturbation theory and average ... The crucial point of hyperpolarization is to transfer the polarization from highly polarized systems to nuclear spins. For example, the unpaired electrons in ...