How is neuronal excitability affected in diseases like Alzheimer's and Parkinson's?

transitive verb : to produce an increase in potential difference across (a biological membrane) intransitive verb : to undergo or produce an increase in ... Hyperpolarisation refers to a group of scientific methods which alter the magnetic properties of materials. This alteration results in large responses in ... Mitochondrial hyperpolarization (MHP), an early event of T-cell activation and death, appears to be mediated through inhibition of F0F1-ATPase or ... Plasma membrane hyperpolarization can lead to calcium influx.18 Therefore, we tested the effects of ivermectin on calcium influx in leukemia cells. OCI-AML2 ... Oct 27, 2021 ... The hyperpolarization technique might not be optimal for detecting effects of insulin in skeletal muscle of anaesthetized animals, which is of significance for ... Jul 5, 2024 ... How to accelerate the acquisition speed and obtain liver images with high spatial resolution: The hyperpolarization level of 13C probe is ... Feb 24, 2022 ... Hyperpolarization ... Hyperpolarization is a term that is used when referring to a process or act resulting in the membrane potential of a cell ... The two general methods of hyperpolarization are dynamic nuclear polarization (DNP) and parahydrogen induced polarization (PHIP). The finding that cAMP facilitates activation of HCN channels by affecting their voltage dependence suggests that the gating mechanism operated by ... Jan 17, 2022 ... We introduce a way to synthesize a fully deuterated, 15 N labelled amino acid derivative and the possibility to polarize the 15 N by means of hydrogenation ...