How does hyperpolarization influence tonic firing?

hyperpolarization, but what is the mechanism by which pinacidil causes the hyperpolarization? As described by the Goldman [11] equation, the membrane ... Jan 24, 2025 ... Mechanism of Solid-State 1H Photochemically Induced Dynamic Nuclear Polarization in a Synthetic Donor–Chromophore–Acceptor at 0.3 T ... Repolarization always leads first to hyperpolarization, a state in which the membrane potential is more negative than the default membrane potential. But soon ... Potassium ions reach equilibrium when the membrane voltage is below −70 mV, so a period of hyperpolarization occurs while the K+ channels are open. Oct 13, 2021 ... September 28, 2021 BSAC Technology Seminar Series Professor Ashok Ajoy, UC Berkeley Hosted by Berkeley Sensor & Actuator Center ... Mar 16, 2022 ... Accurate simulations show astonishingly rich and unexpected dynamics in SABRE/X-SABRE, which we explain with a combination of perturbation theory and average ... Jan 18, 2016 ... being more sensitive, but the transient character of the hyperpolarization requires a continuous and homogeneous supply of polarized gas ... Dec 26, 2023 ... Hyperpolarized 13 C MRI/S allows real-time metabolic changes to be observed non-invasively in living organisms, including cells, tissues, animal models, and ... Mar 27, 2023 ... Hyperpolarized 13C MRI is an emerging powerful molecular imaging strategy that allows safe, non-radioactive, real time and pathway-specific ... Hyperpolarized contrast agents for MRI with long relaxation times. When the nuclear orientation of a material is hyperpolarized by techniques such as dynamic ...