Who were the key researchers involved in the early studies of AMPK?

Under conditions of low energy, AMPK phosphorylates specific enzymes and growth control nodes to increase ATP generation and decrease ATP consumption. In the ... Sep 29, 2020 ... ... AMPK signalling. Nature cell biology 2015, 17(11), 1484. [57] ... activated CA enzyme in the liver tissue while inhibiting CA enzyme in the Apr 20, 2021 ... ... (AMPK), which we demonstrate played essential promalignant activities in ALDOA-expressing cells. Collectively, these findings unveiled vivo ... Mar 17, 2004 ... The enzyme is known as AMP-activated protein kinase, or AMPK. Its activity is regulated by the hormone leptin, which previously was linked ... Mar 6, 2015 ... Background: Nicotinamide phosphoribosyltransferase (NAMPT) is the key enzyme of the NAD salvage pathway starting from nicotinamide. Apr 29, 2021 ... ... enzymes, we evaluated the effect of a SNF1/AMPK inhibitor, dorsomorphin. ... enzyme is tightly regulated. Among the three enzymes tested ... Little is known about the function or mechanism of regulation of the remaining AMPK‐related enzymes. ... enzyme (Figure 2, lanes 10–13). It should be noted ... Metformin enhances the PGC-1α expression and mitochondrial biogenesis possibly at least in part via AMPK phosphorylation in the skeletal muscle. 5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular ... Aug 31, 2016 ... Now, scientists at the Institute for Diabetes and Cancer (IDC) at Helmholtz Zentrum München say they have identified the adenosine monophosphate ...