How does AMPK regulate stem cell quiescence, self-renewal, and differentiation?

Feb 26, 2020 ... AMPK plays a crucial role in regulating Zika virus replication - a study from our lab published recently in the Journal of Immunology. Exercise is perhaps the most powerful physiological activator of AMPK and a unique model for studying its many physiological roles. Apr 1, 2019 ... A compound that is turning out to be one of the major metabolic regulators in the liver, skeletal muscle, fatty acids, and the brain. We show that caloric restriction inhibits progressive loss of heart function, even when started after heart failure is already established. AMPK activity is diminished in adipose tissue of very obese insulin-resistant people, in whom it is associated with increases in oxidative stress and more ... In this review, we will discuss the possible role of AMPK in the beneficial effects of calorie restriction on health and life span. Mar 20, 2020 ... Abstract:The cellular energy sensor AMP-activated protein kinase (AMPK) is a metabolic regulator that mediates adaptation to nutritional ... Apr 1, 2016 ... In this review, we provide a comprehensive summary of both indirect and direct AMPK activators and their modes of action in relation to the structure of AMPK. A key player involved in regulating myocardial metabolism is AMP-activated protein kinase (AMPK), a major regulatory kinase controlling numerous metabolic ... AMPK Signaling Pathway. The AMP-activated protein kinase (AMPK) signaling pathway is one of the master regulators of cellular metabolism that is found in nearly ...