How can targeting AMPK influence the gut microbiome composition and function?

Aug 30, 2024 ... In this study, we utilized an in vitro model to investigate the effects of mechanical loading on AMPK activation and its interaction with the mTOR signaling ... The phospho-AMPK (Thr172) kit is designed for robust cell-based quantification of AMP-activated protein Kinase modulation when phosphorylated on Threonine 172. Feb 26, 2020 ... AMPK plays a crucial role in regulating Zika virus replication - a study from our lab published recently in the Journal of Immunology. 10929-2-AP targets AMPK Alpha in WB, IHC, IF/ICC, IP, ELISA applications and shows reactivity with human, mouse, rat samples. Apr 17, 2024 ... Our data demonstrate that PMF reduction in the intestine is sufficient to initiate locomotor responses to acute food deprivation. In this review, we provide a comprehensive summary of both indirect and direct AMPK activators and their modes of action in relation to the structure of AMPK. We show that caloric restriction inhibits progressive loss of heart function, even when started after heart failure is already established. Apr 7, 2023 ... In fasting, adiponectin increases and stimulates AMPK, leading to the induction of food intake and reduction of energy expenditure. After ... Dec 8, 2021 ... The energy sensor AMP kinase (AMPK) and the master scaffolding protein, AXIN, are two major regulators of biological processes in metazoans. Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism.