What is genetic drift? How do mutations contribute to genetic diseases?

Mutations in the BRAF gene can cause normal cells to become cancerous. BRAF mutations are most commonly found in melanomas, but can occur in other forms of ... Mar 11, 2025 ... PolG disease is caused by inherited mutations in the POLG gene. Currently, over 200 disease-causing POLG mutations are known. POLG ... Tyrosinase (TYR) catalyzes the rate-limiting, first step in melanin production and its gene (TYR) is mutated in many cases of oculocutaneous albinism (OCA1), an ... Feb 10, 2022 ... ... mutation identified. What causes pancreatic cancer? It's probably a combination of things, including genetic predisposition and lifestyle ... Jan 16, 2025 ... Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder. Researchers studying ... Therefore, mutations in different domains cause a range of CF symptoms ... This mutation is caused by the deletion of three base pairs of the CFTR gene ... Mar 11, 2021 ... In a recent breakthrough, researchers have been able to calculate when the JAK2 mutation that causes MPN disease first appeared in two ... While most DNA replicates with fairly high fidelity, mistakes do happen, with polymerase enzymes sometimes inserting the wrong nucleotide or too many or too ... Mutations in the SOD1 gene are the second-most common cause of familial ALS, found in about 10-20% of cases, as well as 1-2% of sporadic ALS cases. Researchers ... Mar 5, 2021 ... Mutations have many possible causes. Some mutations seem to happen spontaneously without any outside influence. They can occur when mistakes are made during ...