What are mutations in genes involved in protein homeostasis and aging?

Feb 10, 2022 ... ... mutation identified. What causes pancreatic cancer? It's probably a combination of things, including genetic predisposition and lifestyle ... Jan 1, 2008 ... This study identifies two new mutations, confirms SCN4A as a common cause of paramyotonia congenita in the UK, and suggests further allelic ... Oct 13, 2023 ... Hemophilia is typically caused by mutations in the genes that provide instructions for making proteins needed for proper blood clotting. Sep 12, 2024 ... JAK2 mutations lead to health conditions, including myeloproliferative neoplasms (MPNs), a type of blood cancer. Many people with MPNs have a JAK2 mutation. Mutations result either from errors in DNA replication or from the damaging effects of mutagens, such as chemicals and radiation, which react with DNA and ... Recently, researchers discovered a new gene, GANAB, that is believed to cause polycystic liver and kidney disease as well. Mutations of the first gene, PKD1, ... Feb 20, 2025 ... Mutations are abnormal changes in the DNA of a gene and can sometimes lead to cancer. Find out common causes. There are two types of these cancer causing genetic mutations: Hereditary; Non-Hereditary. Non-Hereditary Gene Mutations. Most cancers are caused by what is ... Apr 23, 2019 ... What are the behavioral and lifestyle factors that cause cancer? A handful of behavioral factors may lead to genetic mutations and cancer ... Nov 8, 2019 ... Cancer is caused by mutations in our DNA that allow cells to grow uncontrollably – and eventually invade surrounding tissue.