How does natural selection act on mutations?

But though certain mutations have been identified as risk factors for myeloma, multiple myeloma is not thought to be a hereditary disease. That is to say, the ... Aug 28, 2024 ... Mutations in the BRCA genes raise a person's risk for breast, ovarian, and other cancers. May 17, 2005 ... Causes of Elevated Homocysteine Levels. Some people have elevated homocysteine levels (Table 1) caused by a deficiency of B vitamins and folate ... Causes. Thalassemia is caused by mutations in the DNA of cells that make hemoglobin — the substance in red blood cells that carries oxygen throughout your body. Feb 20, 2025 ... Mutations are abnormal changes in the DNA of a gene and can sometimes lead to cancer. Find out common causes. Dec 5, 2019 ... Northwestern Medicine scientists have discovered why a specific genetic mutation causes intellectual disability and autism spectrum disorder in children. This is called a non-truncating PKD1 mutation. Patients with PKD2 mutations not only have a milder disease but a later onset of symptoms which can lead to ... Jan 6, 2025 ... Missense mutations occur when a single nucleotide base in a DNA sequence is swapped for another one, resulting in a different codon and, ... Recently, researchers discovered a new gene, GANAB, that is believed to cause polycystic liver and kidney disease as well. Mutations of the first gene, PKD1, ... Jun 5, 2013 ... We identified four novel heterozygous mutations in MKRN3, the gene encoding makorin RING-finger protein 3, in 5 of the 15 families; both sexes were affected.