How do mutations lead to drug resistance in cancer? What is personalized medicine?

Aug 28, 2024 ... Mutations in the BRCA genes raise a person's risk for breast, ovarian, and other cancers. Oct 16, 2023 ... Let's explore some of the common causes of mutations, which can include everything from external factors like UV radiation and viruses to internal errors ... Jan 18, 2022 ... Most classic Rett syndrome cases are caused by a mutation within the Methylcytosine-binding protein 2 (MECP2) gene. Jun 5, 2013 ... We identified four novel heterozygous mutations in MKRN3, the gene encoding makorin RING-finger protein 3, in 5 of the 15 families; both sexes were affected. Jan 19, 2022 ... There are multiple mutations that are linked to the development of this type of blood cancer, however the most common cause of this cancer is a ... Mar 11, 2021 ... In a recent breakthrough, researchers have been able to calculate when the JAK2 mutation that causes MPN disease first appeared in two ... Tyrosinase (TYR) catalyzes the rate-limiting, first step in melanin production and its gene (TYR) is mutated in many cases of oculocutaneous albinism (OCA1), an ... There are two types of these cancer causing genetic mutations: Hereditary; Non-Hereditary. Non-Hereditary Gene Mutations. Most cancers are caused by what is ... Some genetic diseases, such as cystic fibrosis, are caused by mutations in a single gene. A gene contains DNA “letters” that spell out the instructions to ... Researchers identified a gene on the X chromosome that, when flawed (mutated), causes Duchenne, Becker, and an intermediate form of muscular dystrophies.