What are patch-clamp techniques?

RNA modifications are involved in many aspects of biological functions. RNA modification controls cell fate transition in the mammalian embryonic stem cells ... Introduction: Biomedical experiments in microgravity provide an insight into the fundamental mechanisms of living cells. Not only astronauts benefit from ... To ensure genome stability, mammalian cells employ several DNA repair pathways. Nonhomologous DNA end joining (NHEJ) is the DNA repair process that fixes ... The in vitro mammalian cell gene mutation test can be used to detect gene mutations induced by chemical substances. In this test, the used genetic endpoints ... Robin Chemers Neustein Laboratory of Mammalian Cell Biology and Development ... cellular junctions and enables the cells to form adhesive sheets of ... Here, we systematically analyzed the biodiversity of R2 elements and screened several R2 orthologs capable of full-length gene insertion in mammalian cells. Mammalian cells are gaining popularity in expressing protein as there is more flexibility in pursuing this route. However, unlike plant cells or yeast, ... Dec 31, 2024 ... ... mammalian cells. We expressed these sarabodies and sarabody–GFP modules, purified them as soluble proteins, characterized their binding ... We developed a combinatorial RNA interference (RNAi) based platform for the systematic and quantitative generation of genetic and chemical-genetic interaction ... Sep 27, 2022 ... Here, we report progress on a large-scale synthetic genomics effort to reestablish EAA biosynthetic functionality in mammalian cells.