What is the role of the tumor microenvironment in influencing B cell behavior?

B cells are essential for efficient immune responses and the maintenance of health. However, accumulating evidence points to the involvement of B cells in the ... Jun 12, 2024 ... INTRODUCTION. B cell prolymphocytic leukemia (B-PLL) is a very rare B cell neoplasm comprised of so-called prolymphocytes, typically with ... What the effector cells do is, they turn into antibody-- they turn into these effector B cells-- or sometimes they're called plasma cells. They're going to turn ... Dec 23, 2015 ... Abstract. B cells play a central role in the immunopathogenesis of glomerulonephritides and transplant rejection. B cells secrete antibodies ... May 28, 2019 ... Because we used to think that T cells were the major problem, DMTs often target those cells. But now we see that drugs targeting B cells are ... Screening for common variable immunodeficiency and hyper-IgM syndromes. Assessing B-cell subset reconstitution after stem cell or bone marrow transplant. The role of the CD19/CD21 complex in B cell processing and presentation of complement-tagged antigens. This type of activation produces memory and plasma B cells. Naïve B cells bind to soluble or membrane bound antigens and internalize the antigen. The B cell ... Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL) in the United States and worldwide, accounting for about 22 percent ... The finding gives oncologists a new target for developing immunotherapies: double negative memory B cells, so-called because they are negative for two markers.