What is complement activation by antibodies?

CD20 is a B cell-specific membrane protein and represents an attractive target for therapeutic antibodies. Despite widespread usage of anti-CD20 antibodies ... Apr 3, 2017 ... These immune tolerance mechanisms function at various stages of B cell development. Central tolerance refers to the regulatory mechanisms that ... May 28, 2019 ... Because we used to think that T cells were the major problem, DMTs often target those cells. But now we see that drugs targeting B cells are ... In the article “α4-integrin deficiency in B cells does not affect disease in a T-cell–mediated EAE disease model" by Hussain et al., first published online ... What the effector cells do is, they turn into antibody-- they turn into these effector B cells-- or sometimes they're called plasma cells. They're going to turn ... Apr 21, 2015 ... To date, two models of Breg cell development can be suggested. The first is that Breg cells, similar to thymus-derived Treg cells, are a ... In B-cell lymphoma, some lymphocytes are no longer healthy and do not fight infection. Instead, they grow out of control, crowding out the normal cells and ... Nov 29, 2012 ... CD19 is a biomarker for normal and neoplastic B cells, as well as follicular dendritic cells. CD19 is critically involved in establishing ... Dec 23, 2015 ... Abstract. B cells play a central role in the immunopathogenesis of glomerulonephritides and transplant rejection. B cells secrete antibodies ... What is primary mediastinal large B-cell lymphoma? Primary mediastinal large B-cell lymphoma (PMBCL) is a type of non-Hodgkin lymphoma (NHL). It is sometimes ...