What is allelic exclusion in B cells?

Apr 21, 2015 ... To date, two models of Breg cell development can be suggested. The first is that Breg cells, similar to thymus-derived Treg cells, are a ... Dec 15, 2020 ... BCDTs such as those targeting CD20, CD19 and BAFF are now used to treat autoimmune diseases, including systemic lupus erythematosus and multiple sclerosis. What is primary mediastinal large B-cell lymphoma? Primary mediastinal large B-cell lymphoma (PMBCL) is a type of non-Hodgkin lymphoma (NHL). It is sometimes ... Sep 7, 2017 ... The US Food and Drug Administration granted regular approval to tisagenlecleucel (KYMRIAH, Novartis Pharmaceuticals Corp.) for the treatment of patients up to ... Jan 17, 2025 ... Cutaneous B-cell lymphoma is a cancer that starts in the white blood cells and attacks the skin. It often causes a lump or group of lumps on the skin. Sep 1, 2008 ... A simple definition of B lymphocytes is a population of cells that express clonally diverse cell surface immunoglobulin (Ig) receptors ... The finding gives oncologists a new target for developing immunotherapies: double negative memory B cells, so-called because they are negative for two markers. DLBCL is a common type of fast growing (high grade) NHL. Lymphoma develops when white blood cells called lymphocytes grow out of control. Screening for common variable immunodeficiency and hyper-IgM syndromes. Assessing B-cell subset reconstitution after stem cell or bone marrow transplant. A lymphocyte is a type of white blood cell that is part of the immune system. There are two main types of lymphocytes: B cells and T cells.