What are the potential applications of synthetic biology in B cell engineering?

Dec 23, 2015 ... Abstract. B cells play a central role in the immunopathogenesis of glomerulonephritides and transplant rejection. B cells secrete antibodies ... In B-cell lymphoma, some lymphocytes are no longer healthy and do not fight infection. Instead, they grow out of control, crowding out the normal cells and ... Dec 1, 2018 ... The chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel targets and eliminates CD19-expressing B cells and showed efficacy against B-cell lymphomas. Sep 1, 2008 ... A simple definition of B lymphocytes is a population of cells that express clonally diverse cell surface immunoglobulin (Ig) receptors ... Jul 23, 2019 ... ( A ) Histogram and graph displaying TGFβRI expression and MFI of TGFβR1 staining in HEL-specific cells from spleens, pLNs, mLNs, and PPs of ... Oct 11, 2016 ... ... B cells during pathogenic secondary DENV infections is needed. This ... B cells yield plasmablasts and plasma cells (Seifert et al., 2015. Newborns with congenital athymia may develop autoreactive oligoclonal T-cell expansion resulting in a constellation of symptoms (e.g erythroderma and ... In the article “α4-integrin deficiency in B cells does not affect disease in a T-cell–mediated EAE disease model" by Hussain et al., first published online ... Jan 4, 2024 ... 10:07 Go to channel Understanding Diffuse Large B-Cell Lymphoma with Bruce Cheson, MD, FACP, FAAAS, FASCO Lymphoma Research Foundation Apr 21, 2015 ... Regulatory B (Breg) cells are immunosuppressive cells that support immunological tolerance. Through the production of interleukin-10 (IL-10), IL ...