What are the future prospects for B cell-based therapies?

As a result, VA expanded chronic lymphocytic leukemia to include all chronic B-cell leukemias as related to exposure to Agent Orange or other herbicides during ... Fluorescence in situ hybridization (FISH) is a sensitive method to detect smaller genomic changes associated with various hematological malignancies and solid ... B-cell acute lymphoblastic leukemia, or B-ALL, is a bone marrow and blood cancer. B-ALL occurs at any age but more commonly in children. Feb 19, 2018 ... Targeting of BTK, which has a central role in several signaling pathways in B cells, particularly the BCR, has shown impressive efficacy as ... Jun 13, 2024 ... Mechanisms regulating the induction and durability of B and T cell memory ... Mechanisms of immune cell killing/clearance of infected cells ... Arthur H. and Isabel Bunker Professor of Medicine (Hematology) and Professor of Immunobiology; Director, Center of Molecular and Cellular Oncology; Chief, ... While B-cells produce antibodies to fight infection, T-cells protect people from getting infected by destroying cancerous and infected cells. B-cells are also ... Jan 4, 2024 ... 10:07 Go to channel Understanding Diffuse Large B-Cell Lymphoma with Bruce Cheson, MD, FACP, FAAAS, FASCO Lymphoma Research Foundation When a naïve or memory B cell is activated by an antigen, it proliferates and differentiates into an antibody-secreting effector cell, known as a plasmablast or ... Feb 7, 2025 ... Researchers explore the role of B cells in non-lymphoid tissues, revealing new insights into infections, cancer, potential therapeutic breakthroughs.