What are B cell leukemias and their characteristics?

... B cells might play a critical role in disease pathogenesis. B cells and their antibodies have undisputed roles in health and disease within the airway ... abstract. Sputum examination is a useful noninvasive method to study airway inflammation. We investigated the reproducibility and validity of the ... Feb 7, 2025 ... Researchers explore the role of B cells in non-lymphoid tissues, revealing new insights into infections, cancer, potential therapeutic breakthroughs. Apr 21, 2015 ... Regulatory B (Breg) cells are immunosuppressive cells that support immunological tolerance. Through the production of interleukin-10 (IL-10), IL ... Dec 15, 2020 ... BCDTs such as those targeting CD20, CD19 and BAFF are now used to treat autoimmune diseases, including systemic lupus erythematosus and multiple sclerosis. Centuori SM, Gomes CJ, Kim SS, Putnam CW, Larsen BT, Garland LL, Mount DW, Martinez JD. 2018. Double-negative (CD27IgD) B cells are expanded in NSCLC and ... As a result, VA expanded chronic lymphocytic leukemia to include all chronic B-cell leukemias as related to exposure to Agent Orange or other herbicides during ... A biologic subset of diffuse large B-cell lymphomas with a unique molecular signature or expression profile. Screening for common variable immunodeficiency and hyper-IgM syndromes. Assessing B-cell subset reconstitution after stem cell or bone marrow transplant. Oct 5, 2022 ... This article provides an overview of the mechanisms by which the different human antibody subclasses regulate immunity.