How do B cells migrate to different tissues during an immune response?

Feb 21, 2025 ... A framework, Mal-ID (machine learning for immunological diagnosis), to interpret the variable sequences of B and T cell receptors (BCRs and TCRs) from human ... Dec 15, 2020 ... BCDTs such as those targeting CD20, CD19 and BAFF are now used to treat autoimmune diseases, including systemic lupus erythematosus and multiple sclerosis. Dec 23, 2015 ... Abstract. B cells play a central role in the immunopathogenesis of glomerulonephritides and transplant rejection. B cells secrete antibodies ... Feb 19, 2018 ... Targeting of BTK, which has a central role in several signaling pathways in B cells, particularly the BCR, has shown impressive efficacy as ... CD20 is a B cell-specific membrane protein and represents an attractive target for therapeutic antibodies. Despite widespread usage of anti-CD20 antibodies ... In the article “α4-integrin deficiency in B cells does not affect disease in a T-cell–mediated EAE disease model" by Hussain et al., first published online ... Nov 10, 2021 ... Lymphocytes are a type of white blood cells. They play a critical role in keeping us healthy. Without them, we can't survive. The B Cells have the ability to transform into plasmocytes and are responsible for producing antibodies (Abs). Thus, humoral immunity depends on the B Cells ... Dec 1, 2018 ... The chimeric antigen receptor (CAR) T-cell therapy tisagenlecleucel targets and eliminates CD19-expressing B cells and showed efficacy against B-cell lymphomas. Sep 1, 2008 ... A simple definition of B lymphocytes is a population of cells that express clonally diverse cell surface immunoglobulin (Ig) receptors ...