Therapeutic strategies targeting alternative splicing in specific diseases

Jun 17, 2019 ... 3, 4, 5 Post‐transcriptional regulation is a type of gene expression control at the mRNA level, which includes the regulation of mRNA stability, ... ... posted the information you need. Contact ODNI by Postal Mail. Please send ... One is that information is now extraordinarily difficult to control, which ... Just eight years after their discovery, these genetic scissors have reshaped the life sciences. ... regulate gene activity in cells. Jennifer Doudna's involvement ... Oct 4, 2014 ... ... transcriptional and post-transcriptional regulatory relationships as well as the significant regulatory motifs. ... information to screen ... LEGAL BASIS FOR PROCESSING PERSONAL INFORMATION UNDER THE GENERAL DATA PROTECTION REGULATION (GDPR). 1.1 ... posting a modification notice online. Continued ... Dec 22, 2020 ... For years, RNA half-life has been the only other piece of information that could complement the quantification of total RNA abundance. Nowadays, ... ... information that impedes the translation of `omics ... Results from these efforts have highlighted the prevalence of post-transcriptional regulation ... The emergent and non-linear properties of condensates likely provide a way for the cell to achieve quantitative control of gene expression, post-transcriptional ... Although the majority of post-GWAS efforts have focused on transcriptional regulation of candidate regulatory vari- ants, this study also emphasizes the ... Feb 24, 2022 ... Post-transcriptional regulation can modulate both protein activity and abundance via protein interactions, post-translational modifications, RNA ...