What is the role of mast cells and their mediators in the development of melasma?

▻ Repeated exposure may cause a greenish discoloration of the skin ... low future exposure can cause itching and a skin rash. ▻ Copper may affect ... Do not use. BENLYSTA if the product exhibits discoloration or particulate matter. Instruct the patient not to use the BENLYSTA autoinjector or prefilled syringe ... Sep 10, 2021 ... Skin discoloration may be more bothersome to people of color than the itch and inflammation. It can cause severe anxiety and distress. Eczema ... Oct 12, 2017 ... ... informative for mapping genetic variants associated with skin pigmentation. ... causes the high pigment-1 mutant phenotype. Theor. Appl ... However, it is likely that these people already had systemic lupus, with the skin rash as their main symptom. Drug-induced Lupus Erythematosus. Drug-induced ... Apr 23, 2025 ... From vein disease to sun damage, skin discoloration on legs has many causes. Uncover what's behind your symptoms and effective solutions for ... cause skin pigment change. ▻ Inhaling Asphalt, Oxidized fumes can irritate the nose, throat and lungs. ▻ Exposure to ... Participants' spontaneous responses were coded “correct” if they mentioned: abnormal growth, changing mole, lesions, or abnormal pigment (correct symptom coding ... Jan 11, 2018 ... Vitiligo is a relatively common autoimmune condition causing loss of skin pigment. Around 1 in 100 people in the UK develop vitiligo. It can ... Apr 22, 2025 ... Unexplained rash or itchy skin. Cause: rashes can be caused by a low level of platelets. Some people with blood cancer experience itching, it is ...