How does the unfolded protein response in melanocytes relate to vitiligo?

Apr 29, 2022 ... Several factors can cause the skin to change its pigment. If darker ... Note: The advice provided in this post is intended for informational ... Apr 23, 2025 ... From vein disease to sun damage, skin discoloration on legs has many causes. Uncover what's behind your symptoms and effective solutions for ... Hyperpigmentation is a condition that causes skin to darken. While typically harmless, increased skin pigmentation can be caused by several things. Nov 7, 2024 ... ... causes diffuse hyperpigmentation; Copper (Cu) in Trace Minerals for information on Menkes Syndrome, which is an X-linked syndrome that ... May 9, 2016 ... Yellowstone National Park is the only place in the U.S. where bison have continuously lived since prehistoric times. What makes Yellowstone's ... to transport Oxygen, causing headache, fatigue, dizziness, and a blue color to the skin and lips (methemoglobinemia). Exposure to very high levels can cause ... The three major features of Alkaptonuria are the presence of dark urine, ochronosis, a buildup of dark pigment in connective tissues such as cartilage and skin, ... your nose can become irritated causing a blocked or runny nose; episodes of feeling warm and reddening of the skin (flushing); a risk of falling. Rare side ... However, it is likely that these people already had systemic lupus, with the skin rash as their main symptom. Drug-induced Lupus Erythematosus. Drug-induced ... Apr 4, 2024 ... Without treatment, they may cause ulcers, bleeding, and skin discoloration. ... See additional information. Logo for WebMD.