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What are alarmins?
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what causes ibs to start Informational
- What is substance P?
- Are there any dietary components that might overstimulate these pathways in susceptible individuals? Can alterations in the gut's immune surveillance mechanisms contribute to the start of IBS by leading to inappropriate inflammatory responses?
- What mechanisms might lead to the development of visceral hypersensitivity and could this trigger IBS?
- How might their altered levels or sensitivity contribute to IBS? Can alterations in the gut's resident bacteriophages (viruses that infect bacteria) contribute to the development of IBS by affecting the composition of the gut microbiome?
- How might altered levels contribute to IBS? Can changes in the gut's response to leptin, a satiety hormone, contribute to the onset of IBS symptoms?
- How might their altered signaling contribute to IBS? Can changes in the gut's metabolism of oxalate contribute to the onset of IBS symptoms?
- How might their altered function contribute to IBS? Can alterations in the gut's production of natural killer (NK) cells contribute to the onset of IBS symptoms by affecting immune surveillance?
- Can problems with nutrient absorption play a role in the onset of IBS? Is there a link between food sensitivities and the initial development of IBS?
- How might their dysregulation be involved in IBS? Can changes in the gut's response to bacterial quorum sensing molecules contribute to the onset of IBS by affecting bacterial behavior and host-microbe interactions?
- What are macrophages?
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